If patient with jaundice is Hepatitis-B positive:

Treat the acute phase of jaundice as above.

Treating physician and paramedical staff must be immunized against Hepatitis-B:

Inj. Energix-B 1 ml IM at 0,1, and 6 months, Booster 5 years.

Take universal precautions to protect yourself from needle pricks and destroy all used needles, syringes etc.

Continue Tab. Essentiale (Phospholipids) and Tab. Hepatinic (Ayurvedic) for 6 months as a supportive treatment.

After 6 months

Repeat HBsAg test. In 90% patients will become negative in normal course. Temaining 10% develop chronic hepatitis or a carrier state.

Patients with chronic hepatitis, need specific treatment.

Interferon-alpha 30 million IU/ week (as 10 million IU on alternative days) x 16 weeks (very costly-Rs.12,000/- per week.)

Tab. Lamivudine 100 mg 1 OD x 1year.

If mother is HBsAg positive:

The child should receive.

Inj. Hepatitis B Immunoglobulin 0.06 ml.kg immediately after birth.

Inj. Energix-B 0.5ml 1^st dose, within 12 hrs of birth.

Drugs to avoid in Liver damage:

Quinolones (Like Ciprofloxacin), Macrolodes (Like Erythromycin), Chloramphenicol.

Rifampicin, INH, Pyrazinamide

Steroids, Contraceptive pills, E+P

Metformin, Sulphonyl urea, (Give Insulin)

ACE inhibitors (Like Enalapril)

Anticoagulants, Antipsychotics, Antidepressants.

Gardenal, Carbamazepin, Valproate.

Halothane, Ether, Isoflurane.

Inj. Energix-B

Tab. Essentiale

Tab. Hepatinic

Tab. Lamivudine

Inj. Hepatitis B

Ciprofloxacin