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Disease HYPERLIPIDEMIAS
   
Quotation “Ask not what I can do for my country. Ask what I had for lung”
   
Definition A group of disorders characterized by abnormal values of blood lipids with known association with atherosclerotic vascular disease, especially coronary artery disease.
   
Prognosis Depends upon the type and extent of the abnormality. Patient compliance is a very important decider in the outcome.
   
Treatment

Fat free diet. Avoid Ghee, Ground nut oil. (To reduce cholesterol intake)

 

Use sunflower oil. (To substitute saturated fat by unsaturated fat)

 

Isovac z 1-2 tsp in water x bd (Psyllium Husk fibre to reduce lipid absorption)

 

If LDL and Cholestrol levels are high:

 

Tab. ATORVA 10mg x 1-2 tabs x after dinner or

Tab. SIMVOTIN 10mg x 1-2 tabs x after dinner.

Isovav 1-2 tsp in water x bd (to retard fat absorption)

Questran 9gm sachet x tds (Cholestryamin)

 

If Triglyceride and VLDL levels are high:

 

Cap. LIPICARD 200mg 1 daily or

Tab. Normilip 300mg 1-2 bd x 30min before meals.

 

If not controlled addd-

Tab. Nialio 500mg 1-2 OD x after Lunch.

 

High LDL and Cholestrol= Statins

High Tryglycerida= Fibric acid derivatives + Nicotinic acid.

 

Both are high = Statin + F.A.D (e.g. Sinvotin + LIPICARD)

 

 

Isovav

Questran 9gm sachet

Tab. Normilip


 

ATORVA LIPICARD SIMVOTIN NIALIP 
   
General Measures

Life style modification of great importance and repeatedly stressed in educating the patient on cessation of smoking, minimizing alcohol intake, achievement and maintenance of ideal body weight, aerobic exercise, Yoga, meditation and relaxation exercises.

Control of diabetes, discontinuing thiazide diuretics and beta-blockers with appropriate substitute.
   
Advice to Patient

The importance of controlling lipid levels in preventing atherosclerosis and its dangerous sequelae.

Cessation of smoking, regular exercise, and strict disciplined adherence to diet prescribed.

The necessity for regular checks on serum lipids.

The impotance of monitoring Liver function (those on Statins, and nicotinic acid), and blood glucose and uric acid (those on Nicotinic acid)

If muscle pains or weakness occurs when on therapy, to report to doctor immediately.
   
Follow Up

Lipid levels to be assessed 2-4 times a year depending on nature of lipid disturbance and drugs being used.

For those on statins, liver function tests every three months for the first 15 months, and thereafter periodically.
   
Prevention

Primary, and secondary as detailed above. (See chapter on Post Myocardial infarction)

Prudent diet and weight control for all.
   
Reference From www2.utsouthwestern.edu/humannutrition/Guidelines/
   

 

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