Home | Health News | Themes | Search | Blog | Testimonials | Blood Bank | About Us
 
   
   
   
   
   
   
   
 
testing

 
   
 
Disease NEPHRITIS
   
Definition An immunologically mediated response, (mostly to infection in the tropics, usually post streptococcal and manifesting 1-3 weeks after the infection), and leading to damage to glomeruli that can result in damage to the basement membrane and capillary endothelim.
   
Prognosis Depends on histology and best in those with minimal change GN and focal segmental proliferative GN. Immediate mortality >5%. Long-term prognosis excellent in children with 95% recovering completely and recover of renal function within 8-12 weeks in 955 of patients with post-streptococcal nephritis. Proteinuria might persist for 3 months, and microscopic heamaturia for up to 24 months. More morbidity in adults and those with pre-existing renal disease. Poorer prognosis in those with heavy proteinuria, severe hypertension and significant elevations of creatinine. Proteinuria might persist for 3 months and microscopic heamaturia for up to 24 months.
   
General Measures As detailed under In-patient care.
   
Advice to Patient Strict monitoring after discharge. Restriction of salt, protein, and avoidance of potassium rich foods until oedema, and hypertension clear.
Heamaturia possible after vigorous exercise for 1-2 years.
Abnormal urinalysis may persist for many years.
   
Follow Up Urinalysis and monitoring serum creatinine after ½ 1,2,4,6, and 12 months.
Monitor BP at each visit. There is no need for long-term anti-streptococcal prophylaxis.
Stop follow up when urinalysis is normal.
   
Inadequate Response In cases of development of rapidly progressive Glomerulonephritis, Nephrotic syndrome or end stage renal failure, and calls for nephrologists care.
   
Prevention Aggressive treatment of streptococcal infections with penicillin or erythromycin.
   
Reference From www.emedicine.com /emerg/topic219.html
   

 

SocialTwist Tell-a-Friend
 
 
Home  |   Privacy Policy   |   News Lettter   |   Site Map   |  Disclaimer  |  About Us
   copyright@totalhealthneeds.com   Webmaster:- o3sa.co.in