Indication & Dosage |
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| Oral |
| MANAGEMENT OF THROMBOEMBOLIC DISORDERS |
| Adult:
8-12 mg on the 1st day and 4-8 mg on the 2nd day. Maintenance: 1-8 mg daily given in a single dose at the same time everyday |
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| Precautions |
Bleeding disorders; peptic ulcers; severe wounds; cerebrovascular disorders, bacterial endocarditis; renal or hepatic impairment; lactation. Avoid alcohol. |
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Potentially Life-threatening
Adverse Drug Reactions |
Alopecia; fever, nausea, vomiting, diarrhoea; skin rash; cholestatic liver damage. |
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| Adverse Drug Reactions |
Haemorrhage. |
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| Interactions |
Potentiates hypoglycaemic agents. Bismuth carbonate and Mg reduce absorption. Cimetidine, allopurinol, diuretics and other oral anticoagulants enhance effect. vit K reverses effect. |
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