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ACLENE  ADAPEN  ADARET  ADLENE-A,D  ALENE GEL  DERIVA GEL  ROZAC  WIPLIN GEL 
 
Mechanism of Action
Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.



Indication & Dosage
 
 
Topical/Cutaneous
ACNE
Adult: As 0.1% solution/cream/gel: Apply thinly onto affected areas once daily at night after cleansing.
  
PrecautionsPatients with sunburn, eczema. Pregnancy, lactation. Avoid excessive exposure to sunlight or UV irradiation. Keep away from the eyes, lips, nostrils and mucous membranes. Do not apply to cuts, abrasions, scaly or flaky skin, or patches of sunburned skin. Use with caution with preparations containing sulfur, resorcinol, or salicylic acid.
  
Adverse Drug Reactions Mild skin irritation, scaling, erythema, cutaneous dryness, sensations of stinging and burning, pruritus.
  
InteractionsIncreased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents.
  
   
 

 

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