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Indication & Dosage |
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| Intravenous |
| SHORT-TERM MANAGEMENT OF HEART FAILURE |
| Adult:
Loading dose: 750 mcg/kg by slow inj over 2-3 min (may be repeated after 30 min if necessary). Maintenance: 5-10 mcg/kg/min by infusion |
| Max Dosage: 10 mg/kg in 24 hrs. |
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| Precautions |
Obstructive pulmonary or aortic disease, hypertrophic cardiomyopathy; BP and heart rate monitored during drug administration; fluid and electrolyte balance should be maintained; platelet counts and liver function should be monitored; protect amp from light. Pregnancy and lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
GI disturbances, nausea, vomiting, thrombocytopaenia, hypotension, chest pain, hypersensitivity, myositis, vasculitis, nail discoloration, Inj site pain, decreased tear production. |
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| Adverse Drug Reactions |
Cardiac arrhythmia, hepatotoxicity. |
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| Interactions |
Chemical interaction with precipitation occurs with amrinone and dextrose or furosemide. Thus drug mixing should be avoided. |
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