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Indication & Dosage |
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| Parenteral |
| FALCIPARUM MALARIA |
| Adult:
2.4 mg/kg via IM or IV admin. Repeat 12 hr and 24 hr later, then once daily thereafter. |
| |
| Parenteral |
| FALCIPARUM MALARIA |
| Child:
2.4 mg/kg via IM or IV admin. Repeat 12 hr and 24 hr later, then once daily thereafte |
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| |
|
| Precautions |
Hepatic or renal insufficiency. Pregnancy and lactation. |
| |
|
| Adverse Drug Reactions |
Transient and reversible reticulocytopaenia, drug fever, rash, bradycardia, transient 1st-degree heart block and reversible elevation of serum transaminases. |
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|
| Interactions |
Antimalarial potentiating action seen with mefloquine, primaquine and tetracycline. Additive effect with chloroquine. Antagonistic effect with pyrimethamine and sulphonamides. |
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