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Indication & Dosage |
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Oral |
TREATMENT OF HYPERTENSION |
Adult:
2-4 mg once daily increased to 8 mg once daily, if necessary. |
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Oral |
MANAGEMENT OF ANGINA PECTORIS |
Adult:
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Administration |
Should be taken with food. |
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Precautions |
Elderly. In case of dizziness or lightheadedness, advise patients against handling of heavy machines or working at elevated spots. Reduce dosage gradually while withdrawing drug. Liver function tests. |
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Adverse Drug Reactions |
Palpitation, facial flushing, hot flushes, chest pressure sensation, headache, dizziness, sleepiness, constipation, nausea, abdominal discomfort, oedema, malaise, tinnitus, redness and warm feeling in the fingers, shoulder stiffness, increased frequency of micturition. Hypersensitive reactions e.g. rash and itching. Elevation of SGOT, SGPT, alkaline phosphatase, total bilirubin, creatinine and uric acid. |
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Interactions |
b-blockers or diuretics may enhance BP control. Serum concentrations of digoxin may be increased. Cimetidine may inhibit benidipine metabolism. |
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