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Indication & Dosage |
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Intravenous |
SUSCEPTIBLE INFECTIONS INCLUDING URINARY AND RESP TRACT INFECTIONS, SKIN INFECTIONS, SEPTICAEMIA AND INFECTIONS IN IMMUNOCOMPROMISED PATIENTS |
Adult:
As sulfate: 1-2 g every 12 hr via IV inj over 3-5 minutes or infuse over 20-30 minutes |
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Precautions |
Allergy to penicillin or to cephalosporins; renal impairment, monitor renal and haematological status; pregnancy and lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
Rash, pruritus, urticaria; nausea, vomiting, abdominal pain, diarrhoea; increased plasma levels of ASAT, ALAT, gamma-GT, LDH, bilirubin and/or alkaline phosphatase; interstitial nephritis, acute renal failure; thrombocytopaenia, eosinophilia, haemolytic anaemia, neutropaenia, agranulocytosis; thrombophloebitis, pain at Inj site; convulsions, fever; haemorrhage. |
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Adverse Drug Reactions |
Pseudomembranous colitis. |
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Interactions |
Reduced clearance with probenecid. |
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