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Indication & Dosage |
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| Oral |
| ALLERGIC CONDITIONS INCLUDING URTICARIA, ANGIOEDEMA, RHINITIS, CONJUNCTIVITIS AND PRURITUS |
| Child:
1-2 yr: 1 mg bid, 2-5 yr: 1 mg every 4-6 hr, 6-12 yr: 2 mg every 4-6 hr. Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr). |
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| Oral |
| ALLERGIC CONDITIONS INCLUDING URTICARIA, ANGIOEDEMA, RHINITIS, CONJUNCTIVITIS AND PRURITUS |
| Adult:
4 mg every 4-6 hr. Max: 24 mg daily. |
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| Parenteral |
| ADJUNCT IN THE EMERGENCY TREATMENT OF ANAPHYLACTIC SHOCK |
| Adult:
10-20 mg IM, SC, or slow IV inj over 1 min. Max dose: 40 mg daily. |
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| Parenteral |
| ADJUNCT IN THE EMERGENCY TREATMENT OF ANAPHYLACTIC SHOCK |
| Child:
87.5 mcg/kg SC 4 times daily |
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| Administration |
May be taken with or without food. |
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| Precautions |
Elderly, pylori duodenal obstruction, angle-closure glaucoma, urinary retention, prostatic hyperplasia, epilepsy, renal and hepatic impairment. May affect performance of skilled tasks. BPH, bladder neck obstruction, hypertension. Pregnancy, lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation. |
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| Adverse Drug Reactions |
CV collapse and respiratory failure. |
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| Interactions |
Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opiod analgesics, anxiolytics and antipsychotics. Interaction with alcohol could be dangerous (sedation/excitation). |
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