Indication & Dosage |
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| Oral |
| SHORT-TERM TREATMENT OF ANXIETY DISORDERS |
| Adult:
20-30 mg as a single dose at night or as daily divided doses, increased to 60 mg/day in severe conditions. |
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| Oral |
| SHORT-TERM TREATMENT OF ANXIETY DISORDERS |
| Child:
3-12 yr: 125 mcg/kg bid increased every 5 days. Usual maintenance dose: 250 mcg/kg bid. Max: 500 mcg/kg bid.
Elderly: or debilitated patients: 10-20 mg daily |
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| Oral |
| ADJUNCTIVE THERAPY IN THE MANAGEMENT OF EPILEPSY |
| Adult:
20-30 mg as a single dose at night or as daily divided doses, increased to 60 mg/day in severe conditions. |
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| Oral |
| ADJUNCTIVE THERAPY IN THE MANAGEMENT OF EPILEPSY |
| Child:
3-12 yr: 125 mcg/kg bid increased every 5 days. Usual maintenance dose: 250 mcg/kg bid. Max: 500 mcg/kg bid.
Elderly: or debilitated patients: 10-20 mg daily. |
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| Administration |
May be taken with or without food. |
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| Precautions |
May impair ability to perform skilled tasks and hazardous activities; elderly; renal or hepatic impairment; alcoholics; obesity; withdrawal should be gradual. |
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Potentially Life-threatening
Adverse Drug Reactions |
Constipation, anorexia, nausea; dizziness, fine tremors; worsening of respiratory symptoms in predisposed individuals; ataxia, drowsiness, headache, confusion; loss of libido, motor dysfunction; dependence; visual disturbances and weight gain. |
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| Adverse Drug Reactions |
Respiratory depression. |
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| Interactions |
Increased hepatic clearance of clobazam when administered with phenytoin, phenobarbital or carbamazepine. Cimetidine may increase levels of clobazam. |
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