Indication & Dosage |
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| |
| Oral |
| OEDEMA |
| Adult:
10-40 mg daily or on alternate days, reduce frequency for maintenance. |
| |
| Oral |
| HYPERTENSION |
| Adult:
5-10 mg daily alone or in conjunction with other antihypertensives. |
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| |
|
| Precautions |
Fluid and electrolyte disturbances; hepatic cirrhosis; gout; diabetes mellitus. Elderly; severe heart failure; renal or hepatic impairment. Monitor blood glucose concentrations in patients taking antidiabetics. Pregnancy and lactation. |
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|
| Adverse Drug Reactions |
Electrolyte imbalance; hyperglycaemia; gout; dry mouth; thirst; weakness; muscle pain and cramp; seizures; hypotension; GI disturbances; anorexia; sialadenitis; headache; impotence; yellow vision; hypersensitivity reactions; cholestatic jaundice; pancreatitis; blood dyscrasias; glycosuria; dizziness; photosensitivity reactions, postural hypotension, paraesthesia. |
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|
| Interactions |
Digitalis glycosides; drugs that prolong QT interval; other antihypertensives; competitive muscle relaxants; pressor amines; corticosteroids, corticotrophin; b2-agonists, a-blockers; ACE inhibitors; NSAIDs; alcohol, barbiturates; opioids; lithium; allopurinol; tetracyclines; carbenoxolone; hypoglycaemics. |
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