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Indication & Dosage |
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Oral |
ALLERGIC CONDITIONS (URTICARIA, RHINITIS, CONJUNCTIVITIS) |
Child:
2-5 yr: 0.5 mg; 6-12 yr: 1 mg, dose to be taken every 4-6 hr. |
Max Dosage: Adult: 12 mg daily. Child 6-12 yrs: 6 mg daily; 2-5 |
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Oral |
ALLERGIC CONDITIONS (URTICARIA, RHINITIS, CONJUNCTIVITIS) |
Adult:
2 mg every 4-6 hr. |
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Administration |
May be taken with or without food. |
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Precautions |
Pregnancy; lactation; severe CV disorders; asthma. May impair ability to drive or operate machinery. Angle-closure glaucoma, urinary retention, prostatic hypertrophy, pyloroduodenal obstruction; renal and hepatic impairment; elderly; epilepsy. |
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Adverse Drug Reactions |
Exfoliative dermatitis. Sedation; antimuscarinic effects, CNS depression and disturbances; occasionally, paradoxical CNS stimulation; psychomotor impairment; headache; palpitations and arrhythmias; convulsions, sweating, myalgia, paraesthesias, extrapyramidal symptoms, tremor; sleep and GI disturbances. Rarely, hypersensitivity reactions and blood disorders; tinnitus, hypotension; hair loss. Injections may cause transient hypotension or CNS stimulation and irritation. |
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Interactions |
CNS depressants eg, alcohol, barbiturates, hypnotics, opioid analgesics; anxiolytic sedatives and neuroleptics; other antimuscarinics; MAOIs; betahistine; ototoxic drugs. |
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