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Indication & Dosage |
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| Oral |
| NONPRODUCTIVE COUGH |
| Adult:
10-20 mg every 4 hr, or 30 mg every 6-8 hr. Extended-release oral suspension: 60 mg bid. Max: 120 mg/day. |
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| Oral |
| NONPRODUCTIVE COUGH |
| Child:
6-12 yr: 5-10 mg every 4 hr or 15 mg every 6-8 hr; 2-6 yr: 2.5-5 mg every 4 hr or 7.5 mg every 6-8 hr; up to 2 yr: Individualised dosage. Extended release oral suspension: 6-12 yr: 30 mg bid; 2-6 yr: 15 mg bid. Max: 6-12 yr: 60 mg/day; 2-6 yr: 30 mg/day. |
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| Administration |
May be taken with or without food. |
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| Precautions |
3rd trimester of pregnancy; atopic childn; child <1 yr; sedated or debilitated patients; patients confined to supine position; history of asthma. Moderate to severe renal impairment; liver disease. |
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| Adverse Drug Reactions |
Dizziness, GI disturbances. |
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| Interactions |
Tricyclic antidepressants (TCAs), antipsychotics, anxiolytics and hypnotics, cimetidine, ciprofloxacin, domperidone, metoclopramide, mexiletine, CYP2D6 inhibitors, ritonavir, alcohol. |
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