Indication & Dosage |
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| |
| Oral |
| RELIEF OF MILD TO MODERATE PAIN |
| Adult:
As hydrochloride: 65 mg tid-qid. As napsilate: 100 mg tid-qid. |
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| Administration |
May be taken with or without food. |
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|
| Precautions |
Suicidal patients, hepatic or renal disease; lactation, elderly. |
| |
|
Potentially Life-threatening
Adverse Drug Reactions |
Dizziness, sedation, weakness; nausea, vomiting, constipation; rash, urticaria; visual disturbances; physiological dependence. |
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| Adverse Drug Reactions |
Convulsions in long-term therapy. Cardiac conduction abnormalities and arrhythmias; liver impairment. |
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| Interactions |
Inhibits hepatic metabolism of benzodiazepines, beta-blockers, carbamazepine, phenytoin and warfarin. Increased risk of toxicity when co-administered with ritonavir. Potentiation of depressant effects when used with alcohol or CNS depressants. |
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