Indication & Dosage |
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| Oral |
| BENIGN PROSTATIC HYPERPLASIA |
| Adult:
500 mcg daily (treatment for 6 mth may be required before benefit is obtained). |
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| Administration |
May be taken with or without food. |
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| Precautions |
Excreted in semen therefore use of condom is recommended. Women of childbearing potential should avoid handling dutasteride capsules. Advisable to exclude other causes of benign prostatic hypertrophy (e.g. prostate cancer, infection) before initiating therapy. |
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Potentially Life-threatening
Adverse Drug Reactions |
Concurrent use with CYP3A4 inhibitors such as diltiazem and verapamil may increase serum levels of dutasteride. |
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| Adverse Drug Reactions |
Impotence; decreased libido; ejaculation disorders; breast tenderness and enlargement. |
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