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Indication & Dosage |
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| Oral |
| ENDOMETRIOSIS |
| Adult:
10 mg bid-tid cyclically or continuously. |
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| Oral |
| RECURRENT MISCARRIAGE |
| Adult:
10 mg bid given cyclically until conception, then continuously until wk 20 of pregnancy, after which dose may be gradually reduced. |
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| Oral |
| ENDOMETRIOSISMENSTRUAL DISORDERS EG, MENORRHAGIA |
| Adult:
10 mg bid in a cyclical regimen. |
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| Oral |
| THREATENED MISCARRIAGE |
| Adult:
Initially, 40 mg followed by 10 mg or more every 8 hr, continued for a wk after symptoms are relieved. Reduce dose gradually after that unless symptoms return. |
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| Oral |
| INFERTILITY |
| Adult:
10 mg bid. |
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| Oral |
| ENDOMETRIAL PROTECTION DURING MENOPAUSAL HRT |
| Adult:
10 mg 1-2 times daily in a cyclical regimen or 5 mg daily |
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| Administration |
May be taken with or without food. |
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| Precautions |
Monitor closely for loss of vision, proptosis, diplopia, migraine, signs and symptoms of embolic disorders. CVD or renal impairment, epilepsy, asthma, other conditions which may be aggravated by fluid retention. Lactation. |
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| Adverse Drug Reactions |
Dizziness, nausea, headache, fatigue, emotional lability, irritability; abdominal pain and distention; muskuloskeletal pain. |
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| Interactions |
Carbamazepine, griseofulvin, phenobarbital, rifampicin enhances the clearance of progestogens. |
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