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Indication & Dosage |
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| Oral |
| TUBERCULOSIS |
| Adult:
15-20 mg/kg/day. Max: 1 g/day. |
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| Oral |
| TUBERCULOSIS |
| Child:
Tuberculosis: 15-20 mg/kg/day, given in 2-3 divided doses. Max: 1 g/day. |
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| Oral |
| LEPROSY |
| Adult:
15-20 mg/kg/day. Max: 1 g/day. |
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| Oral |
| LEPROSY |
| Child:
Tuberculosis: 15-20 mg/kg/day, given in 2-3 divided doses. Max: 1 g/day. |
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| Administration |
Should be taken with food. (Take at mealtimes.) |
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| Precautions |
Difficulty in managing DM. Monitor blood glucose, thyroid and visual function. Perform LFT before and during treatment. Caution in patients with psychiatric illness or depression. Pregnancy, lactation. |
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| Adverse Drug Reactions |
Anorexia, excessive salivation, metallic taste, nausea, vomiting, abdominal pain, diarrhoea. Peripheral and/or optic neuritis, psychiatric disturbances eg, depression, anxiety, psychosis, postural hypotension. Jaundice, hepatitis. Thrombocytopenia, skin rashes, stomatitis, gynaecomastia. |
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| Interactions |
May increase serum levels of isoniazid and potentiate the adverse effects of other antituberculous drugs when used concurrently. May cause psychotic reaction when taken with excessive ethanol. |
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