Indication & Dosage |
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Oral |
SEASONAL ALLERGIC RHINITIS |
Adult:
120 mg once daily. |
|
Oral |
SEASONAL ALLERGIC RHINITIS |
Child:
6-11 yr: 30 mg bid |
|
Oral |
CHRONIC IDIOPATHIC URTICARIA |
Adult:
180 mg once daily. |
|
Oral |
CHRONIC IDIOPATHIC URTICARIA |
Child:
6 mth-<2 yr: 15 mg bid; ≥2 yr: 30 mg bid. |
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Administration |
May be taken with or without food. |
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Precautions |
Renal impairment. Pregnancy, lactation; children <6 yr. |
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Adverse Drug Reactions |
Viral infection (cold/flu); headache, dizziness, drowsiness, fatigue; nausea, dyspepsia, dysmenorrhoea. |
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Interactions |
Co-admin with ketoconazole or erythromycin may increase plasma levels of fexofenadine. May increase adverse effects of other anticholinergics and CNS depressants. May increase arrhythmogenic effect of antipsychotic agents (phenothiazines); avoid concurrent usage. May reduce the efficacy of betahistine. Pramlintide may increase the anticholinergic effect of fexofenadine. Bioavailability may be increased by verapamil. Efficacy may be reduced by rifampin. |
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