| |
| |
| Oral |
| SUPERFICIAL MUCOSAL CANDIDIASIS |
| Adult:
50 mg daily increased to 100 mg daily. Recommended treatment duration: 7-14 days (oropharyngeal candidiasis), 14 days (atrophic oral candidiasis associated with dentures), 14-30 days (other mucosal candidal infections including oesophagitis). |
| |
| Oral |
| SUPERFICIAL MUCOSAL CANDIDIASIS |
| Child:
>4 wk: Loading dose: 6 mg/kg followed by 3 mg/kg daily |
| |
| Oral |
| VAGINAL CANDIDIASIS |
| Adult:
150 mg as a single dose |
| |
| Oral |
| CANDIDAL BALANITIS |
| Adult:
150 mg as a single dose. |
| |
| Oral |
| DERMATOPHYTOSIS, PITYRIASIS VERSICOLOR AND CANDIDA INFECTIONS |
| Adult:
50 mg daily for up to 6 wk. |
| |
| Oral |
| CRYPTOCOCCAL INFECTIONS INCLUDING MENINGITIS |
| Adult:
Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Usual treatment duration: At least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. |
| |
| Oral |
| CRYPTOCOCCAL INFECTIONS INCLUDING MENINGITIS |
| Child:
>4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily. |
| |
| Oral |
| SYSTEMIC CANDIDASIS |
| Adult:
Initially, 400 mg followed by 200-400 mg daily. Max: 800 mg daily in severe infections. Usual treatment duration: At least 6-8 wk in cryptococcal meningitis. May also be given via IV infusion. |
| |
| Oral |
| SYSTEMIC CANDIDASIS |
| Child:
>4 wk: 6-12 mg/kg daily; same doses may given every 72 hr in neonates up to 2 wk and every 48 hr in neonates 2-4 wk. Max: 400 mg daily |
| |
| Oral |
| PREVENTION OF RELAPSE FOLLOWING A PRIMARY COURSE OF ANTIFUNGAL TREATMENT FOR ACUTE CRYPTOCOCCAL INFECTIONS IN PATIENTS WITH AIDS |
| Adult:
100-200 mg daily. May also be given intravenously. |
| |
| Oral |
| PROPHYLAXIS OF FUNGAL INFECTIONS IN IMMUNOCOMPROMISED PATIENTS |
| Adult:
50-400 mg daily. May also be given via IV infusion |
| |
| Oral |
| PROPHYLAXIS OF FUNGAL INFECTIONS IN IMMUNOCOMPROMISED PATIENTS |
| Child:
3-12 mg/kg daily; may also be given via IV infusion. For infants <2 wk, doses should be given every 72 hr; 2-4 wk, doses should be given every 48 hr. Max: 400 mg daily, or 12 mg/kg at recommended intervals in infants. |
