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Indication & Dosage |
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Oral |
SHORT-TERM MANAGEMENT OF ANXIETY DISORDERS |
Adult:
50-100 mg qid. |
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Oral |
PRURITUS IN ACUTE AND CHRONIC URTICARIA AND DERMATOSIS |
Adult:
Initially, 25 mg at night increased if required up to 25 mg 3-4 times daily. |
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Oral |
PRURITUS IN ACUTE AND CHRONIC URTICARIA AND DERMATOSIS |
Child:
6 mth-6 yr: 5-15 mg daily, increased to 50 mg/day in divided doses; >6 yr: Initially, 15-25 mg/day, increased up to 50-100 mg/day. |
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Oral |
ADJUNCT TO PRE- OR POSTOPERATIVE SEDATION |
Adult:
50-100 mg.
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Oral |
ADJUNCT TO PRE- OR POSTOPERATIVE SEDATION |
Child:
600 mcg/kg. |
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Intramuscular |
PROMPT CONTROL OF ANXIETY OR AGITATION |
Adult:
Initially, 50-100 mg, may repeat every 4-6 hr if necessary. |
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Administration |
May be taken with or without food. |
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Precautions |
Renal and hepatic impairment; narrow-angle glaucoma; epilepsy; prostatic hypertrophy; bladder neck obstruction; asthma; chronic obstructive pulmonary disease; tasks requiring mental alertness eg, drving or operating machinery. |
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Adverse Drug Reactions |
CNS depression, paradoxical CNS stimulation (childn), dry mouth, thickened resp secretions, constipation, blurring of vision, tachycardia, GI disturbances, headache, hypotension, tinnitus. |
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Interactions |
Potentiates CNS depression by, barbiturates, hypnotics, opioid analgesics, sedatives and neuroleptics. MAOIs, atropine, and tricyclic antidepressants potentiate antimuscarinic effects. Masks ototoxicity of aminoglycoside antibiotics. Increased CNS depression with alcohol or CNS depressants. |
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