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Indication & Dosage |
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| Oral |
| ONCHOCERCIASIS |
| Adult:
3-12 mg (based on 150 mcg/kg) as a single dose every 6-12 mth. |
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| Oral |
| ONCHOCERCIASIS |
| Child:
>5 yrs and >15kg: Same as adult dose. |
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| Oral |
| STRONGYLOIDIASIS |
| Adult:
200 mcg/kg as a single dose or daily on 2 consecutive days. For HIV patients: May need to repeat dose every 2-4 wk. |
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| Administration |
Should be taken on an empty stomach (i.e. At least one hour before food or four hours after food). (Take on an empty stomach.) |
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| Precautions |
Concurrent Loa loa infection, impaired blood-brain barrier function due to infection. |
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| Adverse Drug Reactions |
Diarrhoea, nausea, vomiting, dizziness, pruritus, urticaria, rash, arthralgia, fever, myalgia, asthenia, postural hypotension, tachycardia, oedema, lymphadenopathy, sore throat, cough, headache, somnolence, transient eosinophilia, raised liver enzyme values. |
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| Interactions |
Bioavailability may be increased by alcohol, levamisole. |
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