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Indication & Dosage
 
 
Oral
ADVANCED BREAST CANCER IN POSTMENOPAUSAL WOMEN
Adult: 2.5 mg once daily.
 
Oral
ADJUVANT THERAPY FOR POSTMENOPAUSAL WOMEN WITH HORMONE RECEPTOR POSITIVE EARLY BREAST CANCER.
Adult: 2.5 mg once daily.
   
Administration May be taken with or without food.
   
Precautions Severe renal impairment; severe hepatic impairment; osteoporosis. Caution when driving or operating machinery.
   
Potentially Life-threatening 
Adverse Drug Reactions		 Hot flushes, arthralgia, nausea, vomiting, fatigue, dizziness, headache, dyspepsia, constipation, diarrhoea, anorexia, alopoecia, increased sweating, rash, peripheral oedema, osteoporosis, musculoskeletal pain, vaginal irritation.
   
Adverse Drug Reactions Thromboembolic events.
   
Interactions Plasma levels reduced by tamoxifen.
   
   
 

 
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