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72-HOURS  ECEE 2  G-PILL  HYAN  NORLEVO  PILL 72  T PILL-72 
 



Indication & Dosage
 
 
Oral
CONTRACEPTION
Adult: Monotherapy: 30 or 37.5 mcg daily. Monophasic combined oral contraceptive (COC): 150-250 mcg daily. Triphasic COC: 50-125 mcg daily.
 
Oral
EMERGENCY CONTRACEPTION
Adult: 1.5 mg as soon as possible or within 72 hr of coitus. Alternatively, 750 mcg as soon as possible or within 72 hr of coitus followed by a 2nd dose 12 hr later. Another regimen combines levonorgestrel 500 mcg and ethinylestradiol 100 mcg; may be given within 72 hr of coitus followed by a 2nd dose 12 hr later.
 
Oral
MENOPAUSAL HRT
Adult: As progestogenic component: 75-250 mcg for 10-12 days of a 28-day cycle.
 
Subcutaneous
CONTRACEPTION
Adult: Insert 6 implants (36 mg/implant) under the skin within the first 7 days of the menstrual cycle and replace at intervals of up to 5 yr.
 
Transdermal
MENOPAUSAL HRT
Adult: As combined transdermal patch (releases 10 mcg/24 hr with an oestrogen): Apply once wkly for 2 wk of a 4-wk cycle. Alternatively, a patch releasing 7 or 15 mcg/24 hr with an oestrogen is applied once wkly for continuous HRT.
 
Intrauterine
CONTRACEPTION
Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr.
 
Intrauterine
MENORRHAGIA
Adult: 52 mg released at an initial rate of 20 mcg/day. System is effective for up to 5 yr.
   
Administration May be taken with or without food.
   
Precautions Sex-steroid dependent cancer, past ectopic pregnancy, malabsorption syndromes, functional ovarian cysts, active liver disease, recurrent cholestatic jaundice, history of jaundice in pregnancy, CV or renal impairment, DM, asthma, epilepsy, migraine, conditions aggravated by fluid retention, depression and thromboembolism (high doses); lactation.
   
Potentially Life-threatening 
Adverse Drug Reactions
Menstrual irregularities; nausea, vomiting, headache, dizziness, breast discomfort, gynaecomastia, depression, skin disorders, disturbance of appetite, wt changes, fluid retention, oedema, changes in libido, cholestatic jaundice, hair loss or hirsutism. Benign intracranial hypertension, thrombocytopenic purpura.
   
Adverse Drug Reactions Thrombocytopenia, stroke.
   
Interactions Reduced efficacy with enzyme-inducing drugs; aminoglutethimide. May inhibit ciclosporin metabolism.
   
   
 

 

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