| |
| |
| Oral |
| TREATMENT OF ANXIETY |
Adult:
Initial dose of 2-3 mg daily in 2 or 3 divided doses, usual maintenance range 1-6 mg daily. Largest dose taken at night. Max dose: 10 mg daily.
Elderly: Initial dose of 1-2 mg daily in 2 or 3 divided doses. Adjust as necessary. |
| |
| Oral |
| TREATMENT OF INSOMNIA ASSOCIATED WITH ANXIETY |
| Adult:
1-4 mg as a single dose given at bedtime.
Elderly: 1-2 mg initially, adjust as needed. |
| |
| Oral |
| PREMEDICATION BEFORE SURGERY |
| Adult:
2-3 mg given the night before the operation followed by a smaller dose if necessary, the next morning. Alternatively, 2-4 mg is given 1-2 hr before the operation. |
| |
| Oral |
| PREMEDICATION BEFORE SURGERY |
| Child:
≥5 yr: 0.05-0.1 mg/kg to a max of 4 mg given at least 1 hr before surgery. Same dose may be given the night before either as an additive or replacement dose. |
| |
| Oral |
| PROPHYLAXIS OF SYMPTOMS IN ANTINEOPLASTIC-INDUCED EMESIS |
| Adult:
2.5 mg the evening before and straight after initiation of chemotherapy. Alternatively, 0.5-2 mg every 4-6 hr. |
| |
| Intravenous |
| MANAGEMENT OF STATUS EPILEPTICUS |
| Adult:
4 mg injected slowly (2 mg/min) repeated once if required after 10-15 min |
| |
| Intravenous |
| MANAGEMENT OF STATUS EPILEPTICUS |
| Child:
0.05-0.1 mg/kg |
| |
| Intravenous |
| PREMEDICATION BEFORE SURGERY |
| Adult:
0.044 mg/kg (up to a max of 2 mg) 15-20 min before surgery. Dose may be increased to a max of 4 mg in patients ≤50 yr if necessary. |
| |
| Intravenous |
| TREATMENT OF DELIRIUM. |
| Adult:
0.5-1 mg in combination with haloperidol. |
| |
| Intravenous |
| SEDATION IN CRITICAL CARE |
| Adult:
0.02-0.06 mg/kg every 2-6 hr as inj or 0.01-0.1 mg/kg/hr as continuous IV infusion. |
| |
| Intravenous |
| SEDATION IN CRITICAL CARE |
| Child:
≥2 mth: 0.025-0.05 mg/kg (max 2 mg) every 2-4 hr as intermittent IV infusion or 0.025 mg/kg/hr (to a max of 2 mg/hr) as continuous IV infusion. |
| |
| Intramuscular |
| PROPHYLAXIS OF SYMPTOMS IN ANTINEOPLASTIC-INDUCED EMESIS |
| Adult:
1.5 mg/m2 (max 3 mg) by IV inj over 5 min, admin 45 min before initiation of chemotherapy. |
| |
| Intramuscular |
| PREMEDICATION BEFORE SURGERY |
| Adult:
0.05 mg/kg (up to a max of 4 mg) 2 hr before surgery. |
| |
| Parenteral |
| TREATMENT OF ACUTE OR SEVERE ANXIETY |
| Adult:
0.025-0.03 mg/kg repeated every 6 hr if necessary. |
