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Indication & Dosage |
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| Oral |
| HYPOTENSION SECONDARY TO SPINAL ANAESTHESIA IN OBSTETRIC PATIENTS |
| Adult:
15 mg as a single dose, repeat if needed. |
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| Intramuscular |
| PROPHYLAXIS OF HYPOTENSION SECONDARY TO SPINAL ANAESTHESIA |
| Adult:
30-45 mg administered 10-20 min prior to anaesthesia. |
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| Parenteral |
| MAINTENANCE OF BP IN HYPOTENSIVE STATES SECONDARY TO SPINAL ANAESTHESIA |
| Adult:
IM: 15-30 mg. IV: 30-45 mg as a single dose followed by doses of 30 mg when required to maintain desired BP. Alternatively, as 0.1% IV infusion administered according to patient response. |
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| Precautions |
Patient on MAOIs. For shock due to loss of blood or fluid, give fluid replacement therapy primarily, CVS disease, hypertension, hyperthyroidism, chronic illnesses. Lactation, pregnancy. |
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Potentially Life-threatening
Adverse Drug Reactions |
Drowsiness, incoherence, hallucinations, convulsions, tachycardia. Fear, anxiety, restlessness, tremor, insomnia, confusion, irritability and psychosis. Nausea, vomiting, reduced appetite, urinary retention, dyspnoea, weakness. |
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| Adverse Drug Reactions |
AV block, CNS stimulation. Cerebral haemorrhage and pulmonary oedema, ventricular arrhythmias. |
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| Interactions |
Risk of arrhythmia in patients undergoing anesthesia with cyclopropane and halothane. Antagonises effect of hypotensive agents. Severe HTN with MAOIs and possibly tricyclic antidepressants. Additive vasoconstricting effects with ergot alkaloids, oxytocin. |
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