| |
| |
| Oral |
| SHORT-TERM MANAGEMENT OF INSOMNIA |
| Adult:
7.5-15 mg given at night. |
| |
| Oral |
| PREMEDICATION IN SURGICAL PROCEDURES |
| Child:
≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (<6 yr) may require higher doses/kg than older patients. In obese paediatric patients, calculate dose based on ideal wt. |
| |
| Oral |
| SEDATION |
| Child:
≥6 mth: Single dose of 250-500 mcg/kg, up to a max of 20 mg. Younger patients (<6 yr) may require higher doses/kg than older patients. In obese paediatric patients, calculate dose based on ideal wt. |
| |
| Intravenous |
| PREOPERATIVE SEDATION/ANXIOLYSIS/AMNESIA PRIOR TO OR DURING DIAGNOSTIC, THERAPEUTIC OR ENDOSCOPIC PROCEDURES |
| Adult:
Initially, 1-2.5 mg given over 2 min, increased by increments of 0.5-1 mg at 2-min intervals as needed, until the desired endpoint is achieved. |
| |
| Intravenous |
| PREOPERATIVE SEDATION/ANXIOLYSIS/AMNESIA PRIOR TO OR DURING DIAGNOSTIC, THERAPEUTIC OR ENDOSCOPIC PROCEDURES |
| Child:
6 mth-5 yr: Initial dose of 0.05-0.1 mg/kg given over 2 min, increased by small increments at 2 min intervals. Max total dose 6 mg. 6-12 yr: 0.025-0.05 mg/kg given over 2 min and increased by small increments at 2 min intervals. Max total dose 10 mg. In obese paediatric patients, calculate dose based on ideal wt.
Elderly: Initially 1-1.5 mg given over 2 min, increased by increments of 0.5-1 mg at 2 min intervals as needed. |
| |
| Intravenous |
| FOR INDUCTION OF ANASTHESIA |
| Adult:
150-200 mcg/kg by slow inj in premedicated patients and at least 300 mcg/kg for those who have not received a premedicant. Max 600 mcg/kg. |
| |
| Oral |
| FOR INDUCTION OF ANASTHESIA |
| Child:
>7 yr: 150 mcg/kg. In obese paediatric patients, calculate dose based on ideal wt.
Elderly: 100-200 mcg/kg. |
| |
| Intravenous |
| INDUCTION OF CONTINUOUS SEDATION FOR PATIENTS IN INTENSIVE CARE |
| Adult:
Initially, 30-300 mcg/kg given as infusion over 5 min or by slow IV inj in steps of 1-2.5 mg every 2 min. US guidelines recommend an initial dose of 10-50 mcg/kg repeated at 10-15 min intervals until sedation achieved. Maintenance dose 20-200 mcg/kg/hr as IV inj or infusion. |
| |
| Intramuscular |
| PREMEDICATION IN SURGICAL PROCEDURES |
| Adult:
70-80 mcg/kg (usual dose of 5 mg) given 20-60 min before surgery by deep IM inj. |
| |
| Intramuscular |
| PREMEDICATION IN SURGICAL PROCEDURES |
| Child:
≥1 yr: 80-200 mcg/kg given 20-60 min before surgery by deep IM inj. Max 0.5 mg/kg. Younger patients (<6 yr) may require higher doses per kg than older patients. In obese paediatric patients, calculate dose based on ideal wt.
Elderly: 20-50 mcg/kg given 20-60 min before surgery by deep IM inj. |
