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Indication & Dosage |
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| Oral |
| TYPE 2 DM |
| Adult:
Initially, 25 mg tid, to be taken at the start (with the 1st bite) of each main meal. Increase if necessary after 4-8 wk to usual maintenance dose 50 mg tid. |
| Max Dosage: 100 mg tid. |
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| Precautions |
Hypoglycaemia, renal impairment. |
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| Adverse Drug Reactions |
Abdominal pain, diarrhoea, flatulence, skin rash. To minimise GI effects, treatment may be initiated at 25 mg once daily and increased gradually to three times daily. |
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| Interactions |
Miglitol may significantly reduce the bioavailability of ranitidine and propranolol. Intestinal adsorbents (e.g, charcoal) and digestive enzyme preperations containing carbohydrate-splitting enzymes (e.g, amylase, pancreatin) may reduce the effect and should not be taken concomitantly. |
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