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Indication & Dosage |
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| Topical/Cutaneous |
| DERMATOSES |
| Adult:
Cream/Ointment: Apply thin film to affected area once daily. Lotion: Apply a few drops to affected area once daily. |
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| Topical/Cutaneous |
| DERMATOSES |
| Child:
Cream/Ointment: ≥2 yr: Apply thin film to affected area once daily. Do not use for > 3 wk. Lotion: ≥12 yr: Apply a few drops to affected area once daily. |
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| Nasal |
| PROPHYLAXIS AND TREATMENT OF ALLERGIC RHINITIS |
| Adult:
100-200 mcg in each nostril daily. Maintenance: 50 mcg in each nostril daily. |
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| Nasal |
| PROPHYLAXIS AND TREATMENT OF ALLERGIC RHINITIS |
| Child:
2-11 yr: 50 mcg in each nostril daily; ≥12 yr: 100 mcg in each nostril daily. |
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| Nasal |
| NASAL POLYPS |
| Adult:
100 mcg in each nostril once daily; may increase to bid after 5-6 wk if needed |
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| Inhalation |
| PROPHYLAXIS OF ASTHMA |
| Adult:
Mild to moderate: Initially, 400 mcg once daily. Maintenance: 200 mcg once to bid. Severe: Initially, 400 mcg bid, then titrated to lowest effective dose once controlled. |
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| Inhalation |
| PROPHYLAXIS OF ASTHMA |
| Child:
Mild to moderate: Initially, 400 mcg once daily. Maintenance: 200 mcg once to bid. Severe: Initially, 400 mcg bid, then titrated to lowest effective dose once controlled |
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| Precautions |
Discontinue if irritation or sensitisation occurs. Systemic absorption increases when area of application is extensive or an occlusive dressing is used. Pregnancy and lactation. DM, hepatic and renal diseases, myasthenia gravis, CV disease, ocular diseases, osteoporosis, GI diseases, history of seizure disorders. Not for status asthmaticus or relief of acute bronchospasm. Requires dosage adjustments with thyroid status. May reduce growth velocity in children; monitor growth. Taper withdrawal. |
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Potentially Life-threatening
Adverse Drug Reactions |
Nasal/Oral inhalation: Headache, fatigue, depression; musculoskeletal pain, arthalgia; sinusitis, rhinitis, upper respiratory infection, pharyngitis, cough, epistaxis; viral infection, nasal and oral candidiasis; chest pain; abdominal pain, dry throat, vomiting, diarrhoea, dyspepsia, flatulence, gastroenteritis, nausea, vomiting; dysmenorrhoea; back pain, myalgia; conjunctivitis; earache, otitis media; asthma, bronchitis, dysphonia; nasal irritation, burning and septal perforation; wheezing; nasal ulcers; growth suppression. Topical: Bacterial skin infection, burning, furunculosis, pruritus, skin atrophy, tingling/stinging, folliculitis, moniliasis, paraesthesia, skin depigmentation, rosacea, cataract, growth suppression. |
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| Adverse Drug Reactions |
Adrenal suppression, immunosuppression, Kaposi's sarcoma in prolonged periods, anaphylaxis. |
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| Interactions |
Increased risk of hypokalaemia with amphotericin B, potassium-wasting diuretics. Decreases hypoglycaemic effects of antidiabetic drugs. Increased serum levels with antifungals (imidazole). Increased risk of tendinopathies with fluoroquinolones. |
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