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Indication & Dosage
 
 
Oral
AMOEBIASIS
Adult: 0.5 g bid for 5-10 days
 
Oral
AMOEBIASIS
Adult: 25 mg/kg as a single daily dose for 5-10 days.
 
Oral
AMOEBIC DYSENTERY
Adult: 0.5 g bid for 5-10 days
 
Oral
AMOEBIASIS AMOEBIC DYSENTERY
Adult: 0.5 g bid for 5-10 days
 
Oral
GIARDIASIS
Adult: 0.5 g bid for 5-10 days
 
Oral
GIARDIASIS
Child: 0.5 g bid for 5-10 days
 
Oral
TRICHOMONIASIS
Adult: 0.5 g bid for 5-10 days
 
Oral
TRICHOMONIASIS
Child: 0.5 g bid for 5-10 days
 
Intravenous
SEVERE AMOEBIC DYSENTERY AND AMOEBIC LIVER ABSCESS
Adult: 0.5 g bid for 5-10 days
 
Intravenous
SEVERE AMOEBIC DYSENTERY AND AMOEBIC LIVER ABSCESS
Child: 0.5 g bid for 5-10 days
 
Intravenous
ANAEROBIC BACTERIAL INFECTIONS
Adult: 0.5 g bid for 5-10 days
 
Intravenous
ANAEROBIC BACTERIAL INFECTIONS
Child: 0.5 g bid for 5-10 days
 
Intravenous
PREVENTION OF POSTOPERATIVE ANAEROBIC BACTERIAL INFECTIONS
Adult: 0.5 g bid for 5-10 days
   
Precautions Renal and hepatic impairment. CNS diseases e.g. epilepsy or multiple sclerosis. May impair ability to drive or operate machinery. Pregnancy and lactation.
   
Adverse Drug Reactions Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity, poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness and signs of sensory or mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.

 

   
Interactions Potentiates effect of coumarin-type oral anticoagulants. Prolongs the muscle-relaxant effect of vecuronium bromide.
   
   
 

 

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