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Indication & Dosage |
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| Oral |
| ROUNDWORM INFECTION |
| Adult:
As hydrate: 4.5 g as a single dose repeated once after 14 days. |
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| Oral |
| ROUNDWORM INFECTION |
| Child:
As a single dose, repeated once after 14 days. <1 yr: 120 mg/kg (only upon medical advice), 1-3 yr: 1.5 g, 4-5 yr: 2.25 g, 6-8 yr: 3 g, 9-12 yr: 3.75 g, >12 yr: same as adult dose. |
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| Oral |
| THREADWORM AND PINWORM INFECTION |
| Adult:
As hydrate: 2.25 g once daily for 7 days, 2nd course may be repeated after an interval of 7 days. |
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| Oral |
| THREADWORM AND PINWORM INFECTION |
| Child:
<1 yr: 45-75 mg/kg (only upon medical advice), 1-3 yr: 750 mg, 4-6 yr: 1.125 g, 7-12 yr: 1.5 g, >12 yr: same as adult dose. To be taken once daily for 7 days, 2nd course may be repeated after an interval of 7 days. |
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| Administration |
May be taken with or without food. |
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| Precautions |
Hepatic impairment, neurological conditions, mild to moderate renal impairment. Lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
Nausea, vomiting, colic, abdominal pain, diarrhoea, urticaria, skin rashes, headache, bronchospasm, dizziness, nystagmus, ataxia, paraesthesia, myoclonic contractions, choreiform movements, muscular incoordination (worm wobble), confusion, EEG abnormalities, blurred vision. |
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| Adverse Drug Reactions |
Stevens-Johnson syndrome, bronchospasm and angioedema. |
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| Interactions |
Antagonism if pyrantel and piperazine are used together. Piperazine may potentiate extrapyramidal effects of chlorpromazine and other phenothiazines. |
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