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Indication & Dosage |
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| Oral |
| PARKINSON'S DISEASE |
| Adult:
Monotherapy: 150-250 mg daily in divided doses. In combination with levodopa therapy: 80-140 mg daily. |
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| Oral |
| CIRCULATORY DISORDERS |
| Adult:
50 mg daily or 100 mg daily in 2 divided doses for severe cases. |
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| Administration |
Should be taken with food. (Take at the end of a main meal.) |
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| Precautions |
Raynaud's syndrome, history of psychosis, renal impairment. May cause hypotension in the first few days of treatment. Regular ophthalmological monitoring is recommended. Lactation. |
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| Adverse Drug Reactions |
Nausea, vomiting, dizziness, confusion, drowsiness, hypothermia, dyskinesias, occasional changes in liver function. Raynaud's syndrome or digital vasospasm, leg cramps. |
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| Interactions |
Clonidine and dopamine antagonists eg, phenothiazines and haloperidol may antagonise effects of piribedil. |
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