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Indication & Dosage
 
 
Oral
TREATMENT OF ALLERGIC CONDITIONS
Adult:  As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.
 
Oral
TREATMENT OF ALLERGIC CONDITIONS
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Oral
SHORT-TERM MANAGEMENT OF INSOMNIA
Adult:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Oral
SHORT-TERM MANAGEMENT OF INSOMNIA
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Parenteral
TREATMENT OF ALLERGIC CONDITIONS
Adult:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

Max Dosage:  100 mg.
 
Parenteral
TREATMENT OF ALLERGIC CONDITIONS
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Parenteral
TREATMENT OF NAUSEA AND VOMITING
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

Max Dosage:  100 mg/24 hr.
 
Parenteral
TREATMENT OF NAUSEA AND VOMITING
Adult:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

Max Dosage:  Adult: 100 mg/day.
 
Any Route
PREVENTION AND TREATMENT OF NAUSEA AND VOMITING ASSOCIATED WITH LABYRINTHITIS
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Any Route
PREVENTION AND TREATMENT OF NAUSEA AND VOMITING ASSOCIATED WITH LABYRINTHITIS
Adult:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

Max Dosage:  Adult: 100 mg daily.
 
Any Route
PREVENTION OF MOTION SICKNESS
Child:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

 
Any Route
PREVENTION OF MOTION SICKNESS
Adult:

As hydrochloride: 25 mg at night inreased to 25 mg bid, if needed; alternatively, 10-20 mg bid or tid.

   
Administration May be taken with or without food.
   
Precautions Elderly, glaucoma, epilepsy, CVS disease, impaired liver function, asthma, urinary retention, prostatic hyperplasia, pyloroduodenal obstruction. May cause drowsiness. IV inj must be given slowly to prevent extravasation.
   
Adverse Drug Reactions CNS depression, paradoxical excitation in childn, dryness of mouth, blurring of vision, retention of urine, constipation, glaucoma, tachycardia, headache, hypotension, tinnitus.
   
Interactions Masks ototoxicity of aminoglycoside antibiotics. May enhance the sedative effects of CNS depressants like alcohol, hypnotics, barbiturates and opioids.
   
   
 

 

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