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testing

 
   
RIZACT  RIZATAN 
 



Indication & Dosage
 
 
Oral
ACUTE MIGRAINE ATTACKS
Adult: Initially, 10 mg. If ineffective, 2nd dose should not be taken for the same attack. If symptoms recur after initial response, a further dose of 10 mg may be given. Doses should be separated by at least 2 hr. Max: 20 mg/24 hr. If patient is also taking propanolol, initiate with 5 mg.
Max Dosage:  10 mg/24 hr. Ensure that the 2 drugs are separated
   
Administration May be taken with or without food.
Orally disintegrating tab: May be taken with or without food. (Place on the tongue & allow to dissolve; it can then be swallowed w/ the saliva.)
   
Precautions Elderly; mild to moderate hepatic or renal impairment; coronary artery disease; pregnancy, lactation. May cause drowsiness. History of seizures. Ensure an interval of at least 24 hr after stopping an ergotamine compound and starting a serotonin (5-HT1) agonist.
   
Potentially Life-threatening 
Adverse Drug Reactions
Increased BP, chest pain, palpitation; skin flushing; dyspnoea; nausea, abdominal pain, dry mouth; dizziness, drowsiness, fatigue.
   
Adverse Drug Reactions Toxic epidermal necrolysis.
   
Interactions ncreased serum concentrations with propranolol. Increased risk of vasospastic reactions when used with ergotamine and methysergide. Concurrent use with SSRIs may increase risk of serotonin syndrome.
   
   
 

 

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