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Indication & Dosage |
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| Oral |
| INVASIVE AMOEBIASIS |
| Adult:
1.5 g daily as a single or in divided doses for 5 days. |
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| Oral |
| INVASIVE AMOEBIASIS |
| Child:
30 mg/kg daily for 5 days. |
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| Oral |
| AMOEBIASIS, GIARDIASIS, TRICHOMONIASIS |
| Adult:
2 g as a single daily dose. |
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| Oral |
| AMOEBIASIS, GIARDIASIS, TRICHOMONIASIS |
| Child:
30 mg/kg as a single dose. |
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| Precautions |
Avoid alcohol and disulfiram. Avoid in patients with history of blood disorders. |
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Potentially Life-threatening
Adverse Drug Reactions |
May potentiate anticoagulant effect of warfarin and increase risk of haemorrhage. |
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| Adverse Drug Reactions |
Nausea, gastralgia, change of taste, metallic taste, stomatitis, urticaria, rashes, leucopenia. Rarely vertigo, moderate neurological, digestive disturbances. |
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| Interactions |
Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life. |
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