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Indication & Dosage |
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| Intramuscular |
| SUSCEPTIBLE GRAM-NEGATIVE AND STAPHYLOCOCCAL INFECTIONS |
| Adult:
3 mg/kg daily in 2-3 divided doses. May also be given as IV infusion, if needed. |
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| Topical/Cutaneous |
| PYODERMA |
| Adult:
As 0.1% cream: Apply onto the affected area(s) bid. |
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| Precautions |
Renal or liver impairment, myasthenia gravis, parkinsonism, dehydration, hypotension, pregnancy, lactation. |
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Potentially Life-threatening
Adverse Drug Reactions |
Ototoxicity, nephrotoxicity, neurotoxicity (peripheral neuropathy, confusion, lethargy, hallucination, convulsion and mental depression, occasional respiratory depression), rarely hypersensitivity reaction. |
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| Adverse Drug Reactions |
Acute renal failure especially in combination with other nephrotoxic drugs. |
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| Interactions |
Plasma levels increased by indometacin. Antihistamines (H1-receptor blocker) may mask early signs of ototoxicity. Incompatible with some β-lactam antibiotics. |
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