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testing

 
   
 



Indication & Dosage
 
 
Oral
GROWTH RETARDATION DUE TO CHRONIC RENAL INSUFFICIENCY
Child: 45-50 mcg/kg or 1.4 mg/m2 daily.
 
Oral
HIV-ASSOCIATED WASTING OR CACHEXIA
Adult: 0.1 mg/kg daily at bedtime. May be taken on alternate days for patients at increased risk of adverse effects. Max: 6 mg/day.
 
Oral
TURNER'S SYNDROME
Child: 45-50 mcg/kg or 1.4 mg/m2 daily.
 
Oral
GROWTH HORMONE DEFICIENCY
Child:

25-35 mcg/kg daily. Reassess 9 mth after starting treatment.
 

Elderly: Lower doses may be required.

 
Oral
GROWTH HORMONE DEFICIENCY
Adult: Initially, 6 mcg/kg daily. May increase gradually according to patient response. Max: 12.5 mcg/kg/day. Reassess 9 mth after starting treatment.
 
Oral
PRADER-WILL SYNDROME
Child: 35 mcg/kg or 1 mg/m2 daily. Max: 2.7 mg daily
 
Oral
GROWTH RETARDATION IN CHILDREN WHO WERE BORN SMALL FOR GESTATIONAL AGE
Adult: 35 mcg/kg or 1 mg/m2 daily. Max: 2.7 mg daily
 
Oral
SHORT BOWEL SYNDROME
Adult: 100 mcg/kg/day for 4 wk. Max: 8 mg/day.
 
Oral
CHILDREN WITH SHOX (SHORT STATURE HOMEOBOX-CONTAINING) DEFICIENCY
Child: 50 mcg/kg/day may be used
   
Precautions Monitor thyroid function; benign intracranial hypertension. DM; may require dose reduction in insulin. Pregnancy. Discontinue treatment if there is evidence of tumour growth. Monitoring in patients with scoliosis is recommended due to risk of progression of scoliosis.
   
Adverse Drug Reactions Hypothyroidism, peripheral oedema; headache; muscle and joint pain; benign intracranial hypertension. Loss of glycaemic control in diabetics.
   
Interactions High doses of corticosteroid may inhibit growth-promoting effects of somatropin.
   
   
 

 

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