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Indication & Dosage |
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| Oral |
| ALLERGIC CONDITIONS E.G. RHINITIS AND CONJUNCTIVITIS |
| Adult:
>12 yrs and >50 kg: 60 mg - 120mg in the morning or 60mg bid. Max: 120mg. |
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| Precautions |
Child and elderly. Avoid in patients with cardiac or significant hepatic disease, electrolyte imbalance, or known or suspected prolongation of the QT interval. Lactation, pregnancy. |
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Potentially Life-threatening
Adverse Drug Reactions |
Anxiety, palpitations, insomnia, mild GI distubances, erythema multiforme and galactorrhoea. |
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| Adverse Drug Reactions |
Ventricular arrhythmias including torsades de pointes. Palpitations, dizziness, syncope or convulsions may indicate arrhythmias. Hepatitis. |
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| Interactions |
Increased risk of ventricular arrhythmia with triazole and imidazole antifungals, macrolide antibacterials, streptogramin antibacterials, SSRI, HIV-protease inhibitors and non-nucleoside reverse transcriptase inhibitors, arrhythmogenic drugs, diuretics, astemizole and zileutron. |
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